文章基本信息

标题：Bone Marrow Adipocytes—Role in Physiology and Various Nutritional Conditions in Human and Animal Models
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作者：Katarzyna Piotrowska ; Maciej Tarnowski
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2021
卷号：13
期号：5
页码：1412
DOI：10.3390/nu13051412
出版社：MDPI Publishing
摘要：In recent years, adipose tissue has attracted a lot of attention. It is not only an energy reservoir but also plays important immune, paracrine and endocrine roles. BMAT (bone marrow adipose tissue) is a heterogeneous tissue, found mostly in the medullary canal of the long bones (tibia, femur and humerus), in the vertebrae and iliac crest. Adipogenesis in bone marrow cavities is a consequence of ageing or may accompany pathologies like diabetes mellitus type 1 (T1DM), T2DM, anorexia nervosa, oestrogen and growth hormone deficiencies or impaired haematopoiesis and osteoporosis. This paper focuses on studies concerning BMAT and its physiology in dietary interventions, like obesity in humans and high fat diet in rodent studies; and opposite: anorexia nervosa and calorie restriction in animal models.
关键词：bone marrow adipose tissue; marrow fat; obesity; calorie restriction; dietary interventions; animal models bone marrow adipose tissue ; marrow fat ; obesity ; calorie restriction ; dietary interventions ; animal models