文章基本信息

标题：Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient
本地全文：下载
作者：Mohammed Kaplan ; Michael J. Sweredoski ; João P. G. L. M. Rodrigues 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2020
卷号：117
期号：16
页码：8941-8947
DOI：10.1073/pnas.1916935117
出版社：The National Academy of Sciences of the United States of America
摘要：The bacterial flagellum is an amazing nanomachine. Understanding how such complex structures arose is crucial to our understanding of cellular evolution. We and others recently reported that in several Gammaproteobacterial species, a relic subcomplex comprising the decorated P and L rings persists in the outer membrane after flagellum disassembly. Imaging nine additional species with cryo-electron tomography, here, we show that this subcomplex persists after flagellum disassembly in other phyla as well. Bioinformatic analyses fail to show evidence of any recent horizontal transfers of the P- and L-ring genes, suggesting that this subcomplex and its persistence is an ancient and conserved feature of the flagellar motor. We hypothesize that one function of the P and L rings is to seal the outer membrane after motor disassembly.
关键词：cryo-electron tomography ; flagellar motor ; evolution