文章基本信息

标题：Bioaerosol is an important transmission route of antibiotic resistance genes in pig farms
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作者：Lu Song ; Can Wang ; Guanyu Jiang 等
期刊名称：Environment International
印刷版ISSN：0160-4120
电子版ISSN：1873-6750
出版年度：2021
卷号：154
页码：106559
DOI：10.1016/j.envint.2021.106559
出版社：Pergamon
摘要：Although pig farms are hotspots of antibiotic resistance due to intensive use of antibiotics, little is known about the abundance, diversity and transmission of airborne antibiotic resistance genes (ARGs). This study reports that bioaerosol is an important spread route of ARGs in pig farms. ARGs, mobile genetic elements (MGEs), and bacterial communities were investigated in both air and feces samples during winter and summer. The average concentration of airborne ARGs and MGEs during winter is higher than that during summer when using the ventilation system. The tet M is identified as the predominant airborne ARG with abundance of 6.3 ± 1.2 log copies/m 3 . Clostridium and Streptococcus are two dominant bacteria and several opportunistic pathogens are detected in air samples. High temperature is favorable for more diverse bacterial communities, but relative humidity has negative effects. The wind speed promotes the spread of airborne ARGs. The network analysis results show the average fecal contribution to airborne bacteria is 19.9% and 59.4% during summer and winter, respectively. Horizontal gene transfer plays an important role in the dissemination of airborne ARGs during winter (77.8% possibility), while a lower possibility of 12.0% in summer.
关键词：Bioaerosol ; Antibiotic resistance genes ; Transmission route ; Fecal contribution