文章基本信息

标题：Multi-organ Presentation of Children with COVID-19 Infection in the North of Iran: A Retrospective Study
本地全文：下载
作者：Masood Kiani ; Ali Mohammadpour-Mir ; Hadi Sorkhi 等
期刊名称：International Journal of Pediatrics
印刷版ISSN：2345-5047
电子版ISSN：2345-5055
出版年度：2021
卷号：9
期号：4
页码：13411-13419
DOI：10.22038/ijp.2020.51187.4065
出版社：Mashhad University of Medical Sciences
摘要：Background: COVID-19 can cause various symptoms in children. The aim of the study was evaluation of multi-organ presentation of children with COVID-19 infection in Amirkola Children’s Hospital in Babol, Iran. Materials and Methods: This study was conducted retrospectively and data were extracted from medical records. All children with suspected COVID-19 infection who were referred to Amirkola Children’s Hospital in Babol (north of Iran) from March 4, 2020 to May 30, 2020 were enrolled. Clinical features of the respiratory and digestive system and Multisystem Inflammatory Syndrome in Children ( MIS-c ) were assessed. In all children WBC, RBC, Hb, MCV, Lymphocyte, CRP, ESR, ALT, AST, PT, PTT and platelets were also evaluated. Data analysis was conducted with SPSS software version 16.0. Results: Totally 37 children were recruited to the study. The most common clinical symptoms in children were fever (86.5%), weakness (75.7%) anorexia (73%)abdominal pain (48.6.9%), diarrhea (45.9%) nausea and vomiting (37.8%), cough (32.4%). About 60% and 8% of children had Hb and MCV less than normal levels respectively,So that 80% and 60% of children had abnormal elevations in CRP and ESR, respectively. Also, 32% and 35% of them had an increase in ALT and AST levels respectively and about 40% of them had hypoalbuminemia. Additionally, 7 of 37 (18.9%) children had MIS-c. The result of the study demonstrated that 10/37 (32.4%) of children had pulmonary involvement. Conclusion: In this study gastrointestinal symptoms were more common than respiratory symptoms in children with COVID-19 infection. Also, about one- fifth of children with COVID-19 had MIS-c. Attention to manifestations of organs other than respiratory system in children with COVID-19 infection is necessary.
关键词：Children ; COVID-19 ; Gastrointestinal symptoms ; Respiratory symptoms