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标题：Inhibitory activity of stilbenes against filamentous fungi
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作者：Luce Mattio ; Giorgia Catinella ; Marcello Iriti 等
期刊名称：Italian Journal of Food Safety
电子版ISSN：2239-7132
出版年度：2021
卷号：10
期号：1
页码：1-4
DOI：10.4081/ijfs.2021.8461
出版社：PAGEPress Publications
摘要：Stilbenoids (resveratrol and its derivatives) are secondary metabolites produced by plants as defence mechanism to microbial infection. These compounds are known for their anti-inflammatory action and health benefits in preventing a wide range of disorders (e.g. cancer and cardiovascular diseases). However, their antimicrobial properties are less investigated. A series of 8 stilbenoid compounds were synthesized and their antifungal activity against 19 wild strains of filamentous fungi and yeasts (isolated from the environment and food) was tested in vitro. Using an agar diffusion assay, compounds were tested at the concentration of 100 μg/ml on filamentous fungi and yeasts at 104 CFU/ml. The results showed that tested derivatives possess moderate antifungal activity: in particular, monomeric stilbenoids 3’-hydroxy-pterostilbene and piceatannol, and dimeric stilbenoids (±)-trans-δ-viniferin and pallidol were active against mycotoxigenic fungi.
关键词：stilbenes;resveratrol;antibacterial activity;food-borne fungi