文章基本信息

标题：A Subset of Primary Polydipsia, “Dipsogneic Diabetes Insipidus”, in Apparently Healthy People Due to Excessive Water Intake: Not Enough Light to Illuminate the Dark Tunnel
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作者：Krishnaraju Venkatesan ; Kumarappan Chidambaram ; Premalatha Paulsamy 等
期刊名称：Healthcare
电子版ISSN：2227-9032
出版年度：2021
卷号：9
期号：4
页码：406
DOI：10.3390/healthcare9040406
出版社：MDPI Publishing
摘要：Dipsogenic diabetes insipidus (DDI) is a subtype of primary polydipsia (PP), which occurs mostly in healthy people without psychiatric disease. In contrast, PP is characterized by a polyuria polydipsia syndrome (PPS) associated with psychiatric illness. However, the pathogenesis of DDI is not well established and remains unexplored. In order to diagnose DDI, the patient should exhibit excessive thirst as the main symptom, in addition to no history of psychiatric illness, polyuria with low urine osmolality, and intact urine concentrating ability. Treatment options for DDI remain scarce. On this front, there have been two published case reports with successful attempts at treating DDI patients. The noteworthy commonalities in these reports are that the patient was diagnosed with frequent excessive intake of water due to a belief that drinking excess water would have pathologic benefits. It could therefore be hypothesized that the increasing trend of excessive fluid intake in people who are health conscious could also contribute to DDI. Hence, this review provides an overview of the pathophysiology, diagnosis, and treatment, with a special emphasis on habitual polydipsia and DDI.
关键词：dipsogenic diabetes insipidus; habitual polydipsia; polyuria-polydipsia syndrome; dipsogenic polydipsia; water intoxication; hyponatraemia dipsogenic diabetes insipidus ; habitual polydipsia ; polyuria-polydipsia syndrome ; dipsogenic polydipsia ; water intoxication ; hyponatraemia