文章基本信息

标题：Regulation of Intestinal Inflammation by Soybean and Soy-Derived Compounds
本地全文：下载
作者：Abigail Raffner Basson ; Saleh Ahmed ; Rawan Almutairi 等
期刊名称：Foods
电子版ISSN：2304-8158
出版年度：2021
卷号：10
期号：4
页码：774
DOI：10.3390/foods10040774
出版社：MDPI Publishing
摘要：Environmental factors, particularly diet, are considered central to the pathogenesis of the inflammatory bowel diseases (IBD), Crohn’s disease and ulcerative colitis. In particular, the Westernization of diet, characterized by high intake of animal protein, saturated fat, and refined carbohydrates, has been shown to contribute to the development and progression of IBD. During the last decade, soybean, as well as soy-derived bioactive compounds (e.g., isoflavones, phytosterols, Bowman-Birk inhibitors) have been increasingly investigated because of their anti-inflammatory properties in animal models of IBD. Herein we provide a scoping review of the most studied disease mechanisms associated with disease induction and progression in IBD rodent models after feeding of either the whole food or a bioactive present in soybean.
关键词：inflammatory bowel disease; isoflavone; bioactive compound; isoflavones; inflammation; Crohn’s disease; western diet; plant-based inflammatory bowel disease ; isoflavone ; bioactive compound ; isoflavones ; inflammation ; Crohn’s disease ; western diet ; plant-based