文章基本信息

标题：hybridModels: An R Package for the Stochastic Simulation of Disease Spreading in Dynamic Networks
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作者：Fernando S. Marques ; José H. H. Grisi-Filho ; Marcos Amaku 等
期刊名称：Journal of Statistical Software
印刷版ISSN：1548-7660
电子版ISSN：1548-7660
出版年度：2020
卷号：94
期号：1
页码：1-32
DOI：10.18637/jss.v094.i06
出版社：University of California, Los Angeles
摘要：Disease spreading simulations are traditionally performed using coupled differential equations. However, in the setting of metapopulations, most of the solutions provided by this method do not account for the dynamic topography of subpopulations. Conversely, the alternative approach of individual-based modeling (IBM) may add computational cost and complexity. Hybrid models allow for the study of disease spreading because they combine both aforementioned approaches by separating them across different scales: a local scale that addresses subpopulation dynamics using coupled differential equations and a global scale that addresses the contact between these subpopulations using IBM. We present a simple way of simulating the spread of disease in dynamic networks using the high-level statistical computational language R and the hybridModels package. We built four examples using disease spread models at the local scale in several different networks: an animal movement network; a three-node network, whose model solution using a stochastic simulation algorithm is compared with the ordinary differential equations approach; the commuting of individuals between patches, which we compare with the permanent migration of individuals; and the commuting of individuals within the metropolitan area of São Paulo.
关键词：modeling;dynamic networks;epidemic;stochastic simulation;R.
其他关键词：modeling;dynamic networks;epidemic;stochastic simulation;R