摘要:Exclusive breastfeeding (EBF) is affected by multiple risk factors. Therefore, it is difficult for clinical professionals to identify women who will not practice EBF well and provide subsequent medical suggestions and treatments. This study aimed to apply a decision tree (DT) model to predict EBF at two months postpartum. The socio-demographic, clinical and breastfeeding parameters of 1,141 breastfeeding women from Nanjing were evaluated. Decision tree modelling was used to analyse and screen EBF factors and establish a risk assessment model of EBF. The Chinese version of the Breastfeeding Self-Efficacy Scale (CV-BSES) score, early formula supplementation, abnormal nipples, mastitis, neonatal jaundice, cracked or sore nipples and intended duration of breastfeeding were significant risk factors associated with EBF in the DT model. The accuracy, sensitivity and specificity of the DT model were 73.1%, 75.5% and 66.3%, respectively. The DT model showed similar or better performance than the logistic regression model in assessing the risk of early cessation of EBF before two months postpartum. The DT model has potential for application in clinical practice and identifies high-risk subpopulations that need specific prevention.