文章基本信息

标题：Changes in the salivary electrolytic dynamic after sucrose exposure in children with Early Childhood Caries
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作者：Emerson Tavares de Sousa ; Aline Tavares Lima-Holanda ; Marinês Nobre-dos-Santos 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2020
卷号：10
期号：1
页码：1-8
DOI：10.1038/s41598-020-61128-6
出版社：Springer Nature
摘要：This study sought to explore if the effect of 20% sucrose rinse (SR) on the salivary electrolytic concentration of calcium (Ca2 ), phosphate (Pi) and fluoride (F−) in children with Early Childhood Caries (ECC) is different from healthy children. Here, fifty-eight preschoolers aged 3 to 5 years were divided into 2 groups: caries-free (CF) and with ECC. Changes in saliva flow rate, pH and buffering capacity (BC), as well as in concentrations of Ca2 , Pi, and F−, and the degree of saturation in relation to hydroxyapatite (DSS HAp) and fluorapatite (DSS FAp) were evaluated. The pre-rinse [Ca2 ] was higher in the ECC group in the CF group. A significant increase in [Ca2 ] was demonstrated after SR in the CF group (p = 0.05). The [Pi] was reduced by 18% after SR in the ECC group (p = 0.007). The [F-] reduced in both groups after SR (p < 0.000). There was a moderate positive correlation between [Ca2 ] and the DSS HAp and DSS FAp. Multivariate analysis showed that children with a higher [Ca2 ] in pre-rinse saliva are more likely to have ECC. In conclusion, the effect of a 20% sucrose rinse on the electrolytic concentration of Ca2 , Pi and F- was different when children with ECC were compared with CF children.
关键词：Diagnostic markers