文章基本信息

标题：Nonsteroidal anti-inflammatory drug-induced colopathy: An uncommon cause of positive immunochemical faecal occult blood test in the program for colorectal cancer screening
本地全文：下载
作者：Smolović, Brigita ; Vučković, Ljiljana ; Borozan, Sanja 等
期刊名称：Vojnosanitetski pregled
印刷版ISSN：0042-8450
出版年度：2021
卷号：78
期号：1
页码：105-108
DOI：10.2298/VSP181004004S
出版社：Military Medical Academy, INI
摘要：Introduction. Nonsteroidal anti-inflammatory drug-induced colopathy is an uncommon condition associated with the long-term use of enteric-coated and slow-release nonsteroidal anti-inflammatory drugs. This paper presents a case of colopathy showing no symptoms or signs, discovered by a positive immunochemical faecal occult blood test. Case report. Performed within the framework of the National Program for Screening of Colorectal Cancer, the immunochemical faecal occult blood test was positive in a 56-year-old female patient. The colonoscopy revealed three lesions in the right colon: one erosion-ulceration and two concentric "diaphragm-like" strictures passable by the endoscope. The patient reported that she had been taking diclofenac 100 mg twice a day for the past seven years. After withdrawing the offending drug, the second colonoscopy indicated a marked improvement in the colonic mucosa while the "diaphragm-like" strictures persisted. Conclusion. The cases of nonsteroidal anti-inflammatory drug-induced colopathy are likely to become more frequent. It would be, therefore, advisable to consider the long-term u se of such d rugs as being a possible f actor that leads to mucosal injury, particularly in the right colon, as well as being a rare reason for a positive immunochemical faecal occult blood test.
关键词：colorectal neoplasms; diagnosis; feces; occult blood; colonic diseases; anti-inflammatory agents; treatment outcome