摘要:Now-a-days soft drinks are more favourite refreshment among people all over the world. These non-alcoholic drinks are usually carbonated, sweetened with sugars or artificial sweeteners, edible acids, natural or artificial flavours and colours. Present study was designed to measure and compare the immediate changes in blood glucose levels (BGL) after consuming different soft drinks based on their ingredients, in healthy adult females. Materials and Methods: For this purpose, after recording the postprandial blood glucose concentrations, all participants were randomly divided into 4 groups, were asked to consume 4 different brands of selected soft drinks. At 30, 60, 90 and 120 min of intervals BGL were measured. Results: After 30 min the groups who consumed brand I, III and IV showed a rise in the mean BGL due to the presence of simple sugars, whereas, consumption of brand II containing artificial sweetener did not show such trend, instead mean BGL decreased from baseline values. After 60 min, the groups who consumed brands I, II and IV showed a significant decline in mean BGL and indicated the release of insulin, while a slow reduction in mean BGL was observed in group consuming brand III which showed caffeine-induced decreased insulin sensitivity. In between 60-90 min the mean BGL again raised to maintain blood glucose concentration followed by glucagon release with brands I, II and IV. After 120 min, the mean BGL was lower in groups who consumed brands I, II and III than that of the initial (postprandial) blood glucose concentrations. Conclusion: As all brands of selected soft drinks not only contained different categories of sweeteners but some additives with their health-related harmful effects, so the best approach for patients of diabetes and metabolic disorders is to avoid or limit the intake of soft drinks. However, for normal healthy persons, it is better to consume a drink with minimum artificial additives.