文章基本信息

标题：The Relationship between Serum Levels of Cardiac Enzymes and Junctional Ectopic‏ Tachycardia (JET) after Cardiac Surgery of Congenital Heart Disease
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作者：Mohammad Reza Khalilian ; Mehdi Ebrahimi ; Koroush Vahidshahi 等
期刊名称：International Journal of Pediatrics
印刷版ISSN：2345-5047
电子版ISSN：2345-5055
出版年度：2020
卷号：8
期号：12
页码：12675-12683
DOI：10.22038/ijp.2020.46829.3801
出版社：Mashhad University of Medical Sciences
摘要：Background In this study, we aimed to survey the relationship between serum levels of cardiac enzymes and junctional ectopic ‏ tachycardia (JET) after corrective surgery of congenital heart disease (CHD). Materials and Methods: In this cohort study, 140 children with CHD who were hospitalized in intensive care unit of Shahid Modarres hospital in Tehran, Iran, were divided into case group (the JET group including 37 patients), and control group including 103 patients. These two groups were compared based on the previous studies and collected data. Results: Based on the analysis of the area under the Receiver Operating Characteristic curve, the Creatine Kinase Myocardial Band (CK-MB) level assessment can predict the occurrence of JET after the surgery (area under the curve is 0.849, 95% confidence interval is 0.786- 0.911), and the best cut-off point for it is 95.5 to predict the occurrence of JET. So, CK-MB will diagnose the occurrence of JET with 97.3% sensitivity and 67% specificity ‏ . In the same analysis, the troponin level assessment can predict the occurrence of JET after the surgery (area under the curve is 0.877, 95% confidence interval is 0.821- 0.933). Accordingly, the best cut-off point for the troponin is 45 to predict the occurrence of junctional ectopic ‏ tachycardia which will diagnose it with 97.3% sensitivity, and 72.8% specificity ‏ . Conclusion There is a positive correlation between the occurrence of JET after corrective surgery of CHD and an increase in the level of CK-MB and troponin enzymes. So that the level of CK-MB above 95.5 and the level of troponin above 45 might predict the occurrence of JET in these patients with high accuracy.
关键词：Children ; Cardiac surgery ; Congenital heart disease ; JET