文章基本信息

标题：Gluten and Autism Spectrum Disorder
本地全文：下载
作者：Iain D. Croall ; Nigel Hoggard ; Marios Hadjivassiliou 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2021
卷号：13
期号：2
页码：572
DOI：10.3390/nu13020572
出版社：MDPI Publishing
摘要：An expanding body of literature is examining connections between Autism Spectrum Disorder (ASD) and dietary interventions. While a number of specialist diets have been suggested as beneficial in ASD, gluten has received particularly close attention as a potentially exacerbating factor. Reports exist suggesting a beneficial effect of the gluten-free diet (GFD) in ameliorating behavioural and intellectual problems associated with ASD, while epidemiological research has also shown a comorbidity between ASD and coeliac disease. However, both caregivers and clinicians have expressed an uncertainty of the value of people with ASD going gluten-free, and as the GFD otherwise receives considerable public attention a discussion which focuses specifically on the interaction between ASD and gluten is warranted. In this review we discuss the historical context of ASD and gluten-related studies, and expand this to include an overview of epidemiological links, hypotheses of shared pathological mechanisms, and ultimately the evidence around the use and adoption of the GFD in people with ASD.
关键词：autism spectrum disorder; gluten sensitivity; celiac disease; coeliac disease; review autism spectrum disorder ; gluten sensitivity ; celiac disease ; coeliac disease ; review