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标题：Concentración sérica de vitamina A y su relación con la adiposidad corporal, el estrés oxidativo y los riesgos cardiovasculares en mujeres con ingesta dietética recomendada de vitamina A
其他标题：Serum concentration of vitamin A and its relationship with body adiposity, oxidative stress, and cardiovascular risk in women with recommended dietary intake of vitamin A
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作者：Bento, Cláudia ; Matos, Andréa C ; Cordeiro, Adryana 等
期刊名称：Nutrición Hospitalaria
印刷版ISSN：0212-1611
出版年度：2020
卷号：37
期号：6
页码：1135-1142
DOI：10.20960/nh.03129
出版社：Aula Médica Ediciones
摘要：Background: evidence indicates a role of vitamin A in the regulation of fat mass influencing obesity and cardiovascular diseases. Material and methods: a cross-sectional study in 200 women, paired by age and by the recommended dietary intake of vitamin A. Subjects were divided into four groups according to body mass index (BMI): 80 eutrophic (E), 40 overweight (OW), 40 class I obesity (OI) and 40 class II obesity (OII). Lipid and glycemic profiles were measured and oxidative stress was evaluated through serum concentrations of uric acid, glutathione peroxidase (GSH-Px), and thiobarbituric acid reactive substances (TBARS). Results: the cutoff points for deficiency of serum retinol and β-carotene levels were < 1.05 μmol/L and 40 μg/dL, respectively. For the recommended dietary intake of vitamin A it was 700 μg/day. Retinol and β-carotene deficiency was found in the E group at 5 % and 15 %, respectively, reaching 77.5 % and 82.5 % in the OII group. Conclusions: a correlation was observed between serum concentrations of retinol and β-carotene and glycemic, lipid, and markers of oxidative stress profiles in the groups studied. It was observed that OI and OII subjects who had retinol and β-carotene deficiency presented a risk that was 16 and 20.7 times greater, respectively, of having a diagnosis with DM2 as compared to E subjects with adequate concentrations of vitamin A. Increased demand of vitamin A may be related to increased BMI, body adiposity, and oxidative stress even when a recommended intake of vitamin A is reached.
关键词：Adiposidad corporal;Retinol;β-caroteno;Riesgos cardiovasculares;Estrés oxidativo
其他关键词：Body adiposity;Retinol;β-carotene;Cardiovascular risks;Oxidative stress