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标题：Phytonutrient and Nutraceutical Action against COVID-19: Current Review of Characteristics and Benefits
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作者：Nitida Pastor ; Maria Carmen Collado ; Paolo Manzoni 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2021
卷号：13
期号：2
页码：464
DOI：10.3390/nu13020464
出版社：MDPI Publishing
摘要：The trend toward using phytonutrients and/or nutraceuticals (P/Ns) with the aim of impacting immune health has increased in recent years. The main reason is that properties of P/Ns are associated with possible immunomodulating effects in the prevention and complementary treatment of viral diseases, including COVID-19 and other respiratory infections. In the present review, we assess the scientific plausibility of specific P/Ns for this purpose of preventative and therapeutic interventions against COVID-19, with an emphasis on safety, validity, and evidence of efficacy against other viruses. Five potential candidates have been identified after reviewing available studies (in silico, in vitro, and in vivo) in which certain flavonoids have demonstrated a potential for use as adjuvant therapeutic agents against viral infections, including COVID-19. As these are often better tolerated than pharmacological treatments, their use could be more widely considered if additional detailed studies can validate the existing evidence.
关键词：phytonutrients; nutraceutical; flavonoids; immune system; COVID-19; SARS-CoV-2 phytonutrients ; nutraceutical ; flavonoids ; immune system ; COVID-19 ; SARS-CoV-2