文章基本信息

标题：Composition of Dietary Fatty Acids and Health Risks in Japanese Youths
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作者：Masayuki Okuda ; Aya Fujiwara ; Satoshi Sasaki 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2021
卷号：13
期号：2
页码：426
DOI：10.3390/nu13020426
出版社：MDPI Publishing
摘要：In the overall composition of dietary fatty acids (FAs), the quantity of each FA is interrelated with that of others. We examined the associations between dietary FA composition and cardiometabolic risk in Japanese youths. Risk factors (anthropometric characteristics, serum lipid and liver enzyme levels, and blood pressure) were measured in 5485 junior-high-school students. Dietary intake was assessed using a food frequency questionnaire. The mean saturated FA (SFA), monounsaturated FA (MUFA), omega-6 polyunsaturated FAs (PUFAs), and omega-3 PUFAs intake were 9.6%E, 10.3%E, 6.3%E, and 1.1%E, respectively. In compositional regression analysis controlled for confounders, a high intake of omega-6 PUFAs relative to others was associated with low low-density-lipoprotein cholesterol levels (LDL-C; p = 0.003), and relative SFA intake was associated with high levels of gamma-glutamyl transpeptidase (p = 0.019). Relative omega-3 PUFAs intake was associated with low blood pressure (p = 0.005–0.034) but had unfavorable effects on adiposity and alanine transaminase. Substitutional models showed similar results for omega-6 PUFAs on LDL-C, but MUFA had inconsistent effects on risk factors. The results from the compositional data analysis were consistent with previous studies and clinical practice/knowledge. Focusing on increasing omega-6 PUFAs in Japanese youths could have favorable consequences in the long term.
关键词：cardiometabolic risk; compositional data analysis; Japanese; monounsaturated fatty acids; omega-3 polyunsaturated fatty acids; omega-6 polyunsaturated fatty acids; saturated fatty acids; youths cardiometabolic risk ; compositional data analysis ; Japanese ; monounsaturated fatty acids ; omega-3 polyunsaturated fatty acids ; omega-6 polyunsaturated fatty acids ; saturated fatty acids ; youths