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标题：Assessing the Relationship between Helicobacter pylori and Chronic Kidney Disease
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作者：Koichi Hata ; Teruhide Koyama ; Etsuko Ozaki 等
期刊名称：Healthcare
电子版ISSN：2227-9032
出版年度：2021
卷号：9
期号：2
页码：162
DOI：10.3390/healthcare9020162
出版社：MDPI Publishing
摘要：The relationship between Helicobacter pylori infection and/or gastric disorders and chronic kidney disease (CKD) has not been elucidated. We investigated the relationship between Helicobacter pylori and/or atrophic gastritis (AG) and chronic kidney disease. In total, 3560 participants (1127 men and 2433 women) were eligible for this cross-sectional study. We divided participants into four study groups: with/without Helicobacter pylori infection and with/without AG. The HP ( ) AG (−) group demonstrated a significant association with CKD compared with the HP (−) AG (−) group (adjusted odds ratio, 1.443; 95% confidence interval, 1.047–1.989). In contrast, the HP ( ) AG ( ) group showed significantly lower adjusted odds of CKD than the HP (−) AG (−) group (adjusted odds ratio, 0.608; 95% confidence interval, 0.402–0.920). H. pylori infection without AG might be associated with CKD in these participants. Conversely, the HP ( ) AG ( ) group had lower odds of CKD. Uncovering an association between gastric and renal conditions could lead to development of new treatment strategies.
关键词：atrophic gastritis; chronic kidney disease; Helicobacter pylori ; inter-organ interactions atrophic gastritis ; chronic kidney disease ; Helicobacter pylori ; inter-organ interactions