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  • 标题:Study on the Subacute Toxicity of Anticancer Platinum Complexese
  • 其他标题:개발한 제3세대 항암제의 아만성 독성연구
  • 本地全文:下载
  • 作者:Kwang-Won Joeng ; Young-Soo Rho ; Se-Young Choung
  • 期刊名称:Environmental Health and Toxicology
  • 电子版ISSN:2233-6567
  • 出版年度:1996
  • 卷号:11
  • 期号:2
  • 语种:English
  • 出版社:Korean Society of Environmental Health and Toxicology
  • 摘要:The purpose of this study was to characterise the subacute toxic potency of i. v. administered KHPC-005 and 006. Few test compounds-related toxic effects were observed in body weight gain,clinical signs,urinalysis,hematological parameters and serum biochemical values. Gross necropsy and histopathology revealed no evidance specific toxicity. Our data indicated that no-observed effect level of KHPC-005 and 006 were estimated to be 10 mg/kg and 4 mg/kg in male rats,and 10 mg/kg and 1.33 mg/kg in female rats,respectively.
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