文章基本信息

标题：Study on the Subacute Toxicity of Anticancer Platinum Complexese
其他标题：개발한 제3세대 항암제의 아만성 독성연구
本地全文：下载
作者：Kwang-Won Joeng ; Young-Soo Rho ; Se-Young Choung 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：1996
卷号：11
期号：2
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：The purpose of this study was to characterise the subacute toxic potency of i. v. administered KHPC-005 and 006. Few test compounds-related toxic effects were observed in body weight gain,clinical signs,urinalysis,hematological parameters and serum biochemical values. Gross necropsy and histopathology revealed no evidance specific toxicity. Our data indicated that no-observed effect level of KHPC-005 and 006 were estimated to be 10 mg/kg and 4 mg/kg in male rats,and 10 mg/kg and 1.33 mg/kg in female rats,respectively.