文章基本信息

标题：General Toxicity of Novel Pt ( II ) Complexes in vivo
其他标题：새로운 항암성 백금 ( II ) 착체류의 in vivo 독성연구
本地全文：下载
作者：Kwang-Won Jeong ; Jong-Seok Lim ; Se-Young Choung 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：1995
卷号：10
期号：2
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：The general toxicological study of new platinum(II) compounds,KHPC-002,KHPC-005 and KHPC-006 were investigated in rats. The effects of these Pt(II) complexes on renal,hematopoietic and hepatic system in rats showed lower toxicity compared with cisplatin. In the consideration of the maximal dose of these Pt(II) complexes using in this experiment is 4-8 times higher than cisplatin,these novel compounds will have the less general toxicity in vivo.