文章基本信息

标题：Toxic Effect of Combination of Buprofezin and Carbaryl in Rats
其他标题：Buprofezin과 Carbaryl의 복합독성에 관한 연구
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作者：Sa Uk Hong ; Jong Woo Lee
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：1992
卷号：7
期号：2
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：In this study,it was examined the toxic effects of combination of buprofezin and carbaryl on hematological,biological and enzymetic parameters in rats. The administration of buprofezin or carbaryl both induced the tissue content of cytochrome P-450 and furthermore,the combination of the both increased significantly the liver content of cytochrome P-450 in rat. But cytochrome P-450 and NADPH -cytochrome c reductase activities in kidney were slightly increased. Administration of carbaryl and combination of the both also significantly increased hepatic aniline hydroxylase activity. In addition,in the combination group,glucose-6 -phosphatase and lipid peroxidase activities were changed in the rat liver. Furthermore,cholinesterase was inhibited in rats treated with carbaryl or the combi- nation of buprofezin and carbaryl. The above results suggested that the combined administration of buprofezin and carbaryl can induce more toxic effects than the single administration of buprofezin or carbaryl. .