文章基本信息

标题：Study on the Correlation between Nicotine Concentrations in Environmental Tobacco Smoke and Urinary Cotinine Concentrations of N onsmokers
其他标题：비흡연자의 Nicotine에 대한 노출량과 뇨중 Cotinine 농도의 상관성에 관한 연구
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作者：Jin-Ho Roh ; Dong-Chun Shin ; Jong-Man Kim 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：1990
卷号：5
期号：2
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：Smoking damages nonsmoker' 's health who have been exposed to passive smoking as well as smoker's own health. Passive smoking can cause serious health damage to particular groups,such as the old aged,children and pregnant women. The purpose of this study is to investigate the relationship between nicotine concentrations in environ- mental tobacco smoke (ETS) and urinary cotinine concentrations of nonsmokers exposed to ETS,and to provide basic information related to health risk assessment. The results of this study were summarized as follows: 1. When 180 cigarrette were smoked during 5 hours (high concentrations exposure) in 132 m3 chamber,mean concentrations of nicotine in ETS showed 263.52 μg/m3士51.93. When 45 cigarretts were smoked (low concentrations exposure),it was 69.43土8.96 μg/ 2. The urinary cotinine concentrations of each times (0,2.5,5,17 and 24 hours) in nonsmokers ranged from 0.27~ 12.52 ng/ml in high concentrations exposure and 0.22 ~2.28 ng/ml in low concentrations exposure. Mean while the total urinary cotinine concentrations during 24 hours ranged from 11.6. - 31.65 ng/ml in high concentrations exposure and 3.45~ 5.64 ng/ml in low concentrations exposure. 3. The correlation equation and coefficient between cotinine concentrations in nons- mokers' urine (y) and nicotine concentrations in ETS (x) was y=0.421 +0.0171x and 0:875 (p<0.01) respectively. 4. The quantity of nonsmokers' smoking exposure by passive smoking can be assumed as based on the estimation of nicotine concentrations in ETS by measuring cotinine concentrations of nonsmokers' urine.