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  • 标题:Effect of Perilla Oil Diet on the Immune Response in Mice
  • 其他标题:마우스에 있어서 식이들기름이 면역반응에 미치는 영향
  • 本地全文:下载
  • 作者:Young Keun A hn ; Jung Hoon Kim ; Do Hoon Kim
  • 期刊名称:Environmental Health and Toxicology
  • 电子版ISSN:2233-6567
  • 出版年度:1988
  • 卷号:3
  • 期号:2
  • 语种:English
  • 出版社:Korean Society of Environmental Health and Toxicology
  • 摘要:The effects of perilla oil diet on the immune response in mice have been studied. ICR male mice were divided into 4 groups and were fed on the experimental diet for 4 weeks. Mice were sensitized and challenged with sheep red blood cell (S RBC). Immune response were evaluated by antibody production,Arthus reaction,delayed type hypersensitivity (DTH),Rosette forming cell (RFC) and macrophage activity. The weight of body,liver,thymus and spleen were measured. The body weight was increased but thymus weight was not altered by them. The perilla oil diet decreased the weight of liver and spleen in mice. It reduced antibody production,Arthus reaction,DTH and RFC,macrophage activ- ity. These results showed that the high perilla oil diet decresed more humoral and celluar immune response than the low perilla oil diet. It decreased the phagocytic activity on the reticuloendothelial system in mice.
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