文章基本信息

标题：The Effect of Ginseng Petroleum Ether Fraction on Immunosuppressed Mice by Lead acetate (I) II. Cellular Immune Response and Histological Studies
其他标题：납의 면역독성에 미치는 인삼의 영향 ( II ) II . 세포성면역 및 조직학적 검사
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作者：Hwi Bae Kim ; Young Keun Ahn ; Joo Young Kim 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：1986
卷号：1
期号：1
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：Experiments were performed to investigate the effect of Panax ginseng petroleum ether fraction on delayed type hypersensitivity,rosette formation,phagocytic activity and histophathological influence in lead acetate treated mice. Lead acetate was administered in the drinking water and ginseng pet. ether fraction was injected i.p. Mice were sensitized and challenged with sheep red blood cells. Erythrocyte(E) rosette formation and DTH reaction were significantly depressed in lead acetate treated mice,and those were restored administration of ginseng fraction. Ginseng pet. ether fraction administration did not have any effect on decreased phagocytic activity. Follicular and parafollicular areal destruction of spleen,and destruction of thymus were finded in lead acetate exposed-mice. Small dose of ginseng pet. ether fraction (5 mg/kg,10 mg/kg)i administraction inhibited those histopath- ological changes,but large dose (20 mg/kg) didn't.