文章基本信息

标题：The Effect of Ginseng Petroleum Ether Fraction on Immunosuppressed Mice by Lead acetate (I) I Humoral Immune Response and Biochemical Studies
其他标题：납의 면역독성에 미치는 인삼의 영향 ( I ) I . 체액성면역 및 생화학적 검사
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作者：Hwi Bae Kim ; Young Keun Ahn ; Joo Young Kim 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：1986
卷号：1
期号：1
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：Experiments were performed on mice to investigate the effect of Panax ginseng petroleum ether fraction on the immunotoxicity of lead acet ate. Lead acetate was administered in the drinking water and ginseng p-ether fraction was injected intraperitonally. Mice were sensitized and challenged with sheep red blood cell. Humoral immune responses were evaluated by antibody production and Arthus reaction. Pathotoxicological influences were measured by serum protein, alkaline phosphatase and total cholesterol. The weight of liver,spleen and thymus were measured. Lead acetate exposure significantly decreased hemagglutination titer,hemolysin titer,Arthus reaction,spleen and thymus weight. Ginseng p-ether fraction administra- tion signifticantly restored or potentiated reduced humoral immune response,spleen and thymus weight. Reduced serum A/G ratio,total cholesterol and alkaline phos- phatase activity were restored or increased by ginseng p- ether fraction administration.