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标题：Fish consumption,mercury exposure,and the risk of cholesterol profiles: findings from the Korea National Health and Nutrition Examination Survey 2010-2011
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作者：Yong Min Cho
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：2017
卷号：32
期号：3
DOI：10.5620/eht.e2017014
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：In this study,the associations between mercury (Hg) exposure and cholesterol profiles were analyzed,and increased Hg levels and cholesterol profiles according to the amount of fish consumption were evaluated. Data on levels of blood Hg,the frequency of fish consumption,total blood cholesterol (TC),high-density lipoprotein cholesterol (HDL-C),low-density lipoprotein cholesterol (LDL-C),and triglyceride (TG) in 3951 adults were obtained from the Korea National Health and Nutrition Examination Survey 2010-2011 database. To compare the distribution for each log-transformed indicator,Student’s t-test and analysis of variance were carried out,and the groups were classified according to the frequency of fish consumption through linear regression analysis;the association between Hg level and cholesterol profiles in each group was analyzed. The blood Hg levels (arithmetic mean,median,and geometric mean) for all target participants were 4.59,3.66,and 3.74 µg/L,respectively. The high cholesterol group,low HDL-C group,and high TG group showed a statistically and significantly higher blood Hg level than the low-risk group. In both sexes,as the frequency of fish consumption increased,blood Hg level also increased,but TC,HDL-C,LDL-C,and TG did not show a similar trend. Increased blood Hg level showed a significant association with increased TC and LDL-C. This statistical significance was maintained in the group with less frequent fish consumption (8 times per month) did not show a similar trend. The results of this study suggest that fish consumption increases the level of Hg exposure,and that as the level of Hg exposure increases,the levels of cholesterol profiles increase. However,this study also suggests that the levels of cholesterol profiles in those with frequent fish consumption can be diminished.
关键词：Mercury;Methylmercury;Fish consumption;Cholesterol profiles;Korea National Health and Nutrition Examination Survey