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标题：Association between Low-level Mercury Exposure and Neurobehavioral Functions in Korean Adults Living in a Coastal City
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作者：Rock Bum Kim ; Byoung-Gwon Kim ; Yu-Mi Kim 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：2013
卷号：28
DOI：10.5620/eht.2013.28.e2013015
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：Objectives The aim of this study was to determine the association between low-level mercury exposure and neurobehavioral functions in adults living in coastal regions of Korea. Methods We selected 172 adults aged 20-65 years living in a city in the coastal region of Korea. A sociodemographic survey was conducted,mercury levels in the blood,urine,and hair were measured,and the associations according to computerized neurobehavioral tests were determined using univariate analysis. After adjustment for associated variables,a multivariate linear regression analysis was performed. Results The geometric mean mercury levels in the blood,urine,and hair were 5.41 µg/L (range,0.00-15.84 µg/L),1.17 µg/g-creatinine (range,0.00-32.86 µg/g-creatinine),and 1.37 mg/kg (range,0.42-6.56 mg/kg),respectively. Variables that were associated with simple reaction time according to the neurobehavioral test results were age and urine mercury level. Variables associated with choice reaction time were the recent use of Korean traditional medicine and urine mercury level. Variables associated with the right-hand finger tapping speed test were age,gender,smoking behavior,education level,monthly household income,and urine mercury level. Variables associated with the left-hand finger tapping speed test were age,gender,education level,and urine mercury level. After adjustment for associated variables,there was no significant association between urine mercury level and simple reaction time (β=25.96;p =0.47),choice reaction time (β=50.37;p =0.32),or the number of left-hand finger taps (β=-1.54;p =0.21). However,urine mercury level was significantly associated with the number of right-hand finger taps (β=-3.86;p =0.01). Conclusions We found no evidence that low-level mercury exposure in adults is associated with deficits in neurobehavioral functions. A longer follow-up study is required to confirm this conclusion.
关键词：Adult;Coastal area;Mercury;Neurobehavioral function