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标题：Current Uses and Research Activity Regarding Non-testing Methods Including (Q)SARs in Various Chemical Regulatory Programs
其他标题：국외 화학물질 관리 제도 내에서의 (Q》SARs 및 비-시험 방법 사용과 관련 연구 현황
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作者：Mi-Hee Ha ; Sanghun Kim
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：2009
卷号：24
期号：3
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：To make measurable regulatory decisions of chemicals,it is necessary to consider their efect on the human health and ecosystem. In principle,this is based on relevant toxicity studies conducted by accepted guidelines. However,current regulatory programs in various countries confront challenges related to risk asessment of large numbers of chemicals within the restricted resources and time. Therefore there is a need for more effi- cient approach to limit the number of tests to be conducted. This promotes the development of powerful non- testing methods (e.g. (Q)SARs) and permits to use the predicted data for regulatory purpose. In this article,current status of non-testing methods in various chemical regulatory programs was reviewed in terms of their application and research activity on them. Finally,their usefulness associated with develop- ment of domestic regulatory program was suggested.
关键词：chemicals;regulatory programs;risk assment;non-testing methods