出版社:Korean Society of Environmental Health and Toxicology
摘要:Biomonitoring of nonylphenol (NP),an endocrine disrupting chemical,is required in Koreal to perform its proper regulation. Thus,we analyzed exposure levels of nonlyphenol (NP) in breast milk from the mothers who delivered babies within 10 days (N=325). We analyzed free and total forms of NP in breast milk with LC/MS/MS (LOD,0.5 ppb). In addition,we obtained questionnaires concerning lifestyle from the subject. As results,ranges of toal NP were < L0D-23.4 pg/L (median,< LOD) and the estimated exposure level of the NP was lower than TDI (tolerable daily intake)s. However,we found that the levels of total NP in the mothers, who had some diseases such as thyroid disorders,were higher than those in healthy mothers (sick mothers, N=34,3.51土4.98 ug/L Vs. normal,N=281 207土3.76 μg/L:;p< 0.05). In conclusion,we suggest that expo- sure monitoring of NP should be continuously performed,even though the risks of NP are not elear,yet.