文章基本信息

标题：Toxicity of Phenols to the Nematode Caenorhabditis elegans
其他标题：Caenorhabditis elegans를 이용한 phenol류의 독성 연구
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作者：Kang Sik Jung ; Sun Hee Hyun ; Se Young Choung 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：2006
卷号：21
期号：3
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：Caenorhabditis elegans(C. elegans) is a free-living soil nematode that commonly used as a biological model and recently,much work has been done using C. elegans as a toxicity model. To evaluate the acute toxicity of phenols to C. elegans,worms were subsequently exposed to nine different xenobiotics. This study described lethal toxicity,reproductive toxicity and movement inhibition using 2-propylphenol,4-propylphenol,2-tertbutylphenol,3-tert-butylphenol,4-tert-butylphenol,2-phenylphenol,4-phenylphenol,nonylphenol and 4- dodecylphenol to C. elegans for 24 hr or 72 hr. We found that phenols used in this study were very toxic to C. elegans. The order of lethal toxicity,reproductive toxicity and movement inhibition is as follows. 4-propylphenol¤2-phenylphenol¤2-tert-butylphenol¤2-propylphenol¤nonylphenol¤3-tert-butylphenol¤4-dodecylphenol¤4-tert-butylphenol¤4-phenylphenol.
关键词：Caenorhabditis elegans;phenols;lethal toxicity;reproductive toxicity