文章基本信息

标题：Method Validation for the Simultaneous Analysis of Organophosphorous Pesticides in Blood by GC/MS
其他标题：GC/MS를 이용한 혈액 중 유기인제류 농약의 동시 분석에 관한 방법의 유효화
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作者：Mee Jung Park ; Ja Youl Yang ; Ki Wook Kim 等
期刊名称：Environmental Health and Toxicology
电子版ISSN：2233-6567
出版年度：2005
卷号：20
期号：4
语种：English
出版社：Korean Society of Environmental Health and Toxicology
摘要：The purpose of this study was to provide the standard method for the analysis of organophosphorous pesticides such as chlorpyrifos,diazinon,malathion and parathion in blood. We performed method validation for these pesticides in blood according to EURACHEM (A focus For Analytical Chemistry in Europe) guide. For the analysis of the pesticides,we used solid.phase extraction column (Waters Oasis HLB˓). After the extraction,the supernatants were evaporated to dryness under the nitrogen stream. They were analyzed by gas chromatography/mass spectrometry (GC/MS) after reconstituting with ethanol. Terbufos was used as an internal standard. To validate this method,we performed verification procedures with the following parameters : selectivity,linearity of calibration,accuracy,precision,limit of detection and quantification. Validation data according to Eurachem guide were adequate for our purpose fot the analysis of chlorpyrifos,diazinon, malathion and parathion in blood.
关键词：organophosphorous pesticides;method validation;solid.phase extraction;GC/MS