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标题：EFFECTS OF VITAMIN C APPLICATION ON IFN-Γ,TNF-Α,IL-2 AND IL-6 LEVELS IN ELITE TAEKWONDO ATHLETES
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作者：Süleyman PATLAR ; Ekrem BOYALI ; Saltuk Buğra BALTACI 等
期刊名称：International Journal of Sport, Exercise and Training Sciences
电子版ISSN：2149-8229
出版年度：2017
卷号：3
语种：English
出版社：Balikesir University
摘要：Effects of Vitamin C Application on IFN-γ,TNF-α,IL-2 and IL-6 Levels in Elite Taekwondo Athletes The aim of this study was to investigate the effects of vitamin C application on secretion of cytokine in individuals who do taekwondo sport.This research was carried out on 10 elite taekwondo athletes who were studying in Selçuk University,School of Physical Education and Sports. Their mean age;20.67±0.24 years and mean body weight was;65.45±1.69 kg. Every day 300 mg vitamin C was given to the participants orally during 4 weeks and exhaustive exercise was done until fatigue occurs before and after vitamin E treatment. Before and following the 4 week implementation period,blood samples were taken 4 times from the participants as at rest and fatigue. Interferon gamma (IFN-γ),tumour necrosis factor-alpha (TNF-α),interleukin -2 (IL-2) and interleukin -6 (IL-6) levels were determined by ELISA test kits on taken blood samples. There were no significant differences on the levels of IFN-γ,IL-2 and TNF-α both before and after implementation. There was significant increase on the levels of serum IL-6 at exercise period in comparison with resting period (P<0.05). This increase in on the levels of serum IL-6 at exercise period prior to implementation was prevented by vitamin C application.Results indicated that;vitamin C application did not lead to significant changes on the levels of IFN-γ,TNF-α and IL-2 on individuals who practice taekwondo sport. However,it inhibits the increase in levels of IL-6 at exercise that leads to suppression of cellular immune function.