文章基本信息

标题：Changes in Urinary Titin N-terminal Fragment Concentration after Concentric and Eccentric Exercise
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作者：Shota Yamaguchi ; Katsuhiko Suzuki ; Takayuki Inami 等
期刊名称：Journal of Sports Science and Medicine
印刷版ISSN：1303-2968
出版年度：2020
卷号：19
期号：1
语种：English
出版社：University of Uludag
摘要：We aimed to compare the urinary titin N-terminal fragment (UTF) concentration after concentric and eccentric exercise and to clarify the specific response of UTF to exercise-induced muscle damage (EIMD). Nine healthy young men performed 30 concentric elbow flexion exercises with maximum effort, rested for at least eight weeks, and performed eccentric exercises at the same workload using the same arm. Changes in the maximal voluntary isometric contraction (MVIC), muscle soreness (SOR), range of motion (ROM), serum creatine kinase (CK) activity, and UTF concentrations were recorded before and after for six consecutive days after exercise. There was no significant difference in workload during exercise between the two exercise types. However, serum CK activity increased after eccentric exercise (p < 0.05). Additionally, MVIC, SOR, ROM, and UTF concentration were significantly higher after eccentric exercise than after concentric exercise (p < 0.05). Although workload was the same, the UTF concentration greatly increased after eccentric exercise. Based on these results, we suggest that UTF can be a non-invasive and highly specific biomarker of EIMD.
关键词：Biomarker;exercise-induced muscle damage;delayed onset muscle soreness;validity;non-inversive