文章基本信息

标题：Fructus lycii: A Natural Dietary Supplement for Amelioration of Retinal Diseases
本地全文：下载
作者：Kumari Neelam ; Sonali Dey ; Ralene Sim 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2021
卷号：13
期号：1
页码：246
DOI：10.3390/nu13010246
出版社：MDPI Publishing
摘要：Fructus lycii (F. lycii) is an exotic “berry-type” fruit of the plant Lycium barbarum that is characterized by a complex mixture of bioactive compounds distinguished by their high antioxidant potential. F. lycii is used in traditional Chinese home cooking and in the Chinese Pharmacopeia as an aid to vision and longevity as well as a remedy for diabetes to balance “yin” and “yang” in the body for about two centuries. Although a myriad of bioactive compounds have been isolated from F. lycii, polysaccharides, carotenoids, flavonoids, and phenolics represent the key functional components of F. lycii. F. lycii has been shown to exhibit a wide range of biological activities in experimental settings including antioxidant, anti-inflammatory, antiapoptotic, and neuroprotective effects. Despite its medicinal role dating back to the eighteenth century in the Far East and robust evidence of beneficial effects on ocular health and retinal diseases originating mainly from studies in animal models, the role of F. lycii in the clinical management of retinal diseases is yet to be established. This article comprehensively reviews the literature germane to F. lycii and retinal diseases with particular emphasis on age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, which are commonly seen in clinical practice.
关键词：Fructus lycii ; carotenoids; antioxidants; age-related macular degeneration; diabetic retinopathy; retinitis pigmentosa Fructus lycii ; carotenoids ; antioxidants ; age-related macular degeneration ; diabetic retinopathy ; retinitis pigmentosa