文章基本信息

标题：Four New Pregnane-10,2-carbolactones from an Epipolasis sp. Marine Sponge
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作者：Unwoo Kang ; Dongdong Wang ; Heidi R. Bokesch 等
期刊名称：Chemical and Pharmaceutical Bulletin
印刷版ISSN：0009-2363
电子版ISSN：1347-5223
出版年度：2021
卷号：69
期号：1
页码：48-51
DOI：10.1248/cpb.c20-00128
出版社：The Pharmaceutical Society of Japan
摘要：Four new pregnane steroids, 3β,4β,16β-trihydroxypregna-5,17-diene-10,2-carbolactone ( 1 ), 16β-acetoxy-3β,4β-dihydroxypregna-5,17-diene-10,2-carbolactone ( 2 ), 12β-acetoxy-3β,4β,16β-trihydroxypregna-5,17-diene-10,2-carbolactone ( 3 ), and 12β,16β-diacetoxy-3β,4β-dihydroxypregna-5,17-diene-10,2-carbolactone ( 4 ) were isolated from an extract of an Epipolasis sp. marine sponge. The structures of the new compounds were determined by extensive NMR spectroscopic analysis and comparison with data from previously reported compounds.
关键词：pregnane steroid;carbolactone;marine sponge;Epipolasis;structure elucidation