文章基本信息

标题：Production of Optically Active Hexahydrocurcumin by Human Intestinal Bacterium in Vitro
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作者：Toshio Niwa ; Shin-ichiro Yokoyama ; Mika Mochizuki 等
期刊名称：Biological and Pharmaceutical Bulletin
印刷版ISSN：0918-6158
电子版ISSN：1347-5215
出版年度：2021
卷号：44
期号：1
页码：136-139
DOI：10.1248/bpb.b20-00584
出版社：The Pharmaceutical Society of Japan
摘要：A hexahydrocurcumin-producing bacterium named 2a1-2b was isolated from human feces. It was observed that the bacterium had more than 99% similarity with Enterococcus avium ATCC14025 T according to 16S ribosomal DNA (rDNA) sequence. The strain 2a1-2b produced optically active 5 R -hexahydrocurcumin (enantiomeric excess (e.e.) > 95%) from tetrahydrocurcumin but not from curcumin. Our results showed that intestine is an important place for producing hexahydrocurcumin.
关键词：hexahydrocurcumin;microflora;optical activity;curcumin