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标题：Therapeutic Potential of Natural Products in Treatment of Cervical Cancer: A Review
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作者：Seung-Hyeok Park ; Minsun Kim ; Somi Lee 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2021
卷号：13
期号：1
页码：154
DOI：10.3390/nu13010154
出版社：MDPI Publishing
摘要：Cervical cancer is the fourth most common cancer among women worldwide. Though several natural products have been reported regarding their efficacies against cervical cancer, there has been no review article that categorized them according to their anti-cancer mechanisms. In this study, anti-cancerous natural products against cervical cancer were collected using Pubmed (including Medline) and google scholar, published within three years. Their mechanisms were categorized as induction of apoptosis, inhibition of angiogenesis, inhibition of metastasis, reduction of resistance, and regulation of miRNAs. A total of 64 natural products suppressed cervical cancer. Among them, Penicillium sclerotiorum extracts from Cassia fistula L., ethanol extracts from Bauhinia variegate candida, thymoquinone obtained from Nigella sativa, lipid-soluble extracts of Pinellia pedatisecta Schott., and 1′S-1′-acetoxychavicol extracted from Alpinia conchigera have been shown to have multi-effects against cervical cancer. In conclusion, natural products could be attractive candidates for novel anti-cancer drugs.
关键词：cervical cancer; dietary natural products; apoptosis; angiogenesis; metastasis; resistance; microRNA cervical cancer ; dietary natural products ; apoptosis ; angiogenesis ; metastasis ; resistance ; microRNA