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标题：Uremic Sarcopenia and Its Possible Nutritional Approach
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作者：Annalisa Noce ; Giulia Marrone ; Eleonora Ottaviani 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2021
卷号：13
期号：1
页码：147
DOI：10.3390/nu13010147
出版社：MDPI Publishing
摘要：Uremic sarcopenia is a frequent condition present in chronic kidney disease (CKD) patients and is characterized by reduced muscle mass, muscle strength and physical performance. Uremic sarcopenia is related to an increased risk of hospitalization and all-causes mortality. This pathological condition is caused not only by advanced age but also by others factors typical of CKD patients such as metabolic acidosis, hemodialysis therapy, low-grade inflammatory status and inadequate protein-energy intake. Currently, treatments available to ameliorate uremic sarcopenia include nutritional therapy (oral nutritional supplement, inter/intradialytic parenteral nutrition, enteral nutrition, high protein and fiber diet and percutaneous endoscopic gastrectomy) and a personalized program of physical activity. The aim of this review is to analyze the possible benefits induced by nutritional therapy alone or in combination with a personalized program of physical activity, on onset and/or progression of uremic sarcopenia.
关键词：uremic sarcopenia; physical activity; hemodialysis; nutritional supplementation; intra-dialytic parenteral nutrition; ω-3 polyunsaturated fatty acids uremic sarcopenia ; physical activity ; hemodialysis ; nutritional supplementation ; intra-dialytic parenteral nutrition ; ω-3 polyunsaturated fatty acids