文章基本信息

标题：Factors in Early Feeding Practices That May Influence Growth and the Challenges That Arise in Growth Outcomes Research
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作者：Veronica Fabrizio ; Veronika Shabanova ; Sarah N. Taylor 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：7
页码：1939-1950
DOI：10.3390/nu12071939
出版社：MDPI Publishing
摘要：Growth in preterm infants is associated with improved outcomes during both the initial hospitalization and long-term. A single center investigation evaluated preterm infant in-hospital growth trajectory and how it related to early nutritional practices as a way to identify areas for quality improvement. Infants born <34 weeks’ gestational age and with discharge at or prior to 40 weeks’ gestational age were included and were divided into quartiles based on their change in weight z-score through hospitalization. Early nutritional factors were compared between the lowest and highest growth quartiles. Although the highest growth quartile experienced less days of parenteral nutrition and higher enteral caloric density in the first week, as the data was analyzed, potential statistical pitfalls became apparent. Therefore, the aim of this study was to investigate selection bias and cohort effect related to both the inclusion criteria for this cohort as well as the inherent challenges in comparison of preterm infant growth trajectories by standard fetal growth charts.
关键词：preterm; growth; z -score; nutrition preterm ; growth ; z -score ; nutrition