文章基本信息

标题：Lutein Supplementation for Eye Diseases
本地全文：下载
作者：Long Hin Li ; Jetty Chung-Yung Lee ; Ho Hang Leung 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：6
页码：1721-1747
DOI：10.3390/nu12061721
出版社：MDPI Publishing
摘要：Lutein is one of the few xanthophyll carotenoids that is found in high concentration in the macula of human retina. As de novo synthesis of lutein within the human body is impossible, lutein can only be obtained from diet. It is a natural substance abundant in egg yolk and dark green leafy vegetables. Many basic and clinical studies have reported lutein’s anti-oxidative and anti-inflammatory properties in the eye, suggesting its beneficial effects on protection and alleviation of ocular diseases such as age-related macular degeneration, diabetic retinopathy, retinopathy of prematurity, myopia, and cataract. Most importantly, lutein is categorized as Generally Regarded as Safe (GRAS), posing minimal side-effects upon long term consumption. In this review, we will discuss the chemical structure and properties of lutein as well as its application and safety as a nutritional supplement. Finally, the effects of lutein consumption on the aforementioned eye diseases will be reviewed.
关键词：age-related macular degeneration; antioxidant; carotenoid; diabetic retinopathy; myopia; cataract; nutrition; retina; retinopathy of prematurity; xanthophyll age-related macular degeneration ; antioxidant ; carotenoid ; diabetic retinopathy ; myopia ; cataract ; nutrition ; retina ; retinopathy of prematurity ; xanthophyll