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标题：The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis
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作者：Anna Alakoski ; Kaisa Hervonen ; Eriika Mansikka 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：4
页码：1060-1069
DOI：10.3390/nu12041060
出版社：MDPI Publishing
摘要：The treatment of choice for dermatitis herpetiformis (DH), a cutaneous manifestation of coeliac disease, is a life-long gluten-free diet (GFD). In a GFD, wheat, rye and barley should be strictly avoided, but the role of oats is more controversial. This study aimed to investigate the safety and long-term quality of life and health effects of oat consumption in 312 long-term treated DH patients. Baseline data were gathered from patient records and follow-up data from questionnaires or interviews, and validated questionnaires were used to assess quality of life. We found that altogether 256 patients (82%) were consuming oats as part of their GFD at the follow-up. Long-term follow-up data showed that there were no differences in the presence of long-term illnesses, coeliac disease complications or the usage of medication between those consuming and not consuming oats. However, oat consumers had a better quality of life and reported ongoing gastrointestinal symptoms less frequently (4% vs 19%, p = 0.004) at the follow-up than those not consuming oats. The study established that oats are safe for DH patients and in the long-term seem to improve the quality of life of DH patients.
关键词：dermatitis herpetiformis; coeliac disease; gluten-free diet; oats; quality of life; complications; follow-up dermatitis herpetiformis ; coeliac disease ; gluten-free diet ; oats ; quality of life ; complications ; follow-up