文章基本信息

标题：Nutrition and the Immune System: A Complicated Tango
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作者：Carina Venter ; Stefanie Eyerich ; Tara Sarin 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：3
页码：818-832
DOI：10.3390/nu12030818
出版社：MDPI Publishing
摘要：Enthusiasm exists for the potential of diet to impact the immune system, prevent disease and its therapeutic potential. Herein, we describe the challenge to nutrition scientists in defining this relationship through case studies of diets and nutrients in the context of allergic and autoimmune diseases. Moderate-quality evidence exists from both human intervention and observational studies to suggest that diet and individual nutrients can influence systemic markers of immune function and inflammation; numerous challenges exist for demonstrating the impact of defined diets and nutrient interventions on clearly influencing immune-mediated-clinical disease endpoints. A growing body of evidence suggests that further consideration of dietary patterns, immune system and gut microbiome composition and function, and subsequent epigenetic modifications are needed to improve our understanding of diet–immune system interactions.
关键词：nutrition; omega-3 fatty acids; fiber; immune system; microbiome nutrition ; omega-3 fatty acids ; fiber ; immune system ; microbiome