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标题：Effects of a Combination of Water-Soluble Coenzyme Q10 and Collagen on Skin Parameters and Condition: Results of a Randomised, Placebo-Controlled, Double-Blind Study
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作者：Katja Žmitek ; Janko Žmitek ; Mirjam Rogl Butina 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：3
页码：618-630
DOI：10.3390/nu12030618
出版社：MDPI Publishing
摘要：Skin is a complex and dynamic organ that provides a protective interface between the external environment and the body; changes in skin appearance are often the first visible signs of aging. It is well established that nutrients and other bioactive substances have important roles in the structure and functions of human skin; however, the effects of dietary supplementation of such bioactives are much less investigated. The objective of this randomised, double-blind placebo-controlled study was to investigate the effects of liquid food supplement, characterised by a combination of water-soluble coenzyme Q10 (Q10Vital®) and collagen, on dermal density and other skin parameters in comparison to placebo. The trial was performed on 34 healthy women aged 40–65 that received either the test product (n = 17) or the placebo (n = 17) for twelve weeks. Measurements and assessments of skin parameters were performed at baseline and after 12 weeks of intervention. We observed improved dermis density, reduced periorbital wrinkle area and the total wrinkle score, and improved skin smoothness. On the other hand, changes in skin hydration, dermis thickness, transepidermal water loss (TEWL) and viscoelasticity were not significant.
关键词：Coenzyme Q10; Q10Vital; CoQ10; collagen peptides; skin health; dermis density Coenzyme Q10 ; Q10Vital ; CoQ10 ; collagen peptides ; skin health ; dermis density