文章基本信息

标题：A Delayed Morning and Earlier Evening Time-Restricted Feeding Protocol for Improving Glycemic Control and Dietary Adherence in Men with Overweight/Obesity: A Randomized Controlled Trial
本地全文：下载
作者：Evelyn B. Parr ; Brooke L. Devlin ; Bridget E. Radford 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：2
页码：505-525
DOI：10.3390/nu12020505
出版社：MDPI Publishing
摘要：We determined the effects of time-restricted feeding (TRF; 8 h/d) versus extended feeding (EXF; 15 h/d) on 24-h and postprandial metabolism and subjective opinions of TRF in men with overweight/obesity. In a randomized crossover design, 11 sedentary males (age 38 ± 5 y; BMI: 32.2 ± 2.0 kg/m2) completed two isoenergetic diet protocols for 5 days, consuming meals at 1000, 1300 and 1700 h (TRF) or 0700, 1400 and 2100 h (EXF). On Day 5, participants remained in the laboratory for 24 h, and blood samples were collected at hourly (0700–2300 h) then 2-hourly (2300–0700 h) intervals for concentrations of glucose, insulin and appetite/incretin hormones. Structured qualitative interviews were conducted following completion of both dietary conditions and investigated thematically. Total 24-h area under the curve (AUCtotal) [glucose] tended to be lower for TRF versus EXF (−5.5 ± 9.0 mmol/L/h, p = 0.09). Nocturnal glucose AUC was lower in TRF (−4.2 ± 5.8 mmol/L/h, p = 0.04), with no difference in waking glucose AUC or AUCtotal for [insulin]. Attitudes towards TRF were positive with improved feelings of well-being. Barriers to TRF were work schedules, family commitments and social events. Compared to extended feeding, short-term TRF improved nocturnal glycemic control and was positively perceived in men with overweight/obesity.
关键词：glucose; insulin; diet; obesity; appetite; acceptability; fasting; dietary patterns; metabolism glucose ; insulin ; diet ; obesity ; appetite ; acceptability ; fasting ; dietary patterns ; metabolism