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标题：Reviewing the Composition of Vaginal Microbiota: Inclusion of Nutrition and Probiotic Factors in the Maintenance of Eubiosis
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作者：Antonio Barrientos-Durán ; Ana Fuentes-López ; Adolfo de Salazar 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：2
页码：419-448
DOI：10.3390/nu12020419
出版社：MDPI Publishing
摘要：The vaginal microbiota has importance in preserving vaginal health and defending the host against disease. The advent of new molecular techniques and computer science has allowed researchers to discover microbial composition in depth and associate the structure of vaginal microbial communities. There is a consensus that vaginal flora is grouped into a restricted number of communities, although the structure of the community is constantly changing. Certain Community-State Types (CSTs) are more associated with poor reproductive outcomes and sexually transmitted diseases (STDs) meanwhile, CSTs dominated by Lactobacillus species—particularly Lactobacillus crispatus—are more related to vaginal health. In this work, we have reviewed how modifiable and non-modifiable factors may affect normal vaginal microbiota homeostasis—including sexual behavior, race or ethnicity, and hygiene. Special interest has been given to how the use of probiotics, diet intake, and use of hormone replacement therapies (HRTs) can potentially impact vaginal microbiota composition.
关键词：vaginal microbiome; bacterial communities; vaginal dysbiosis; bacterial vaginosis; risk factors; nutrition; probiotics; hormone replacement therapy vaginal microbiome ; bacterial communities ; vaginal dysbiosis ; bacterial vaginosis ; risk factors ; nutrition ; probiotics ; hormone replacement therapy