文章基本信息

标题：Role of Overweight and Obesity in Gastrointestinal Disease
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作者：Sara Emerenziani ; Michele Pier Luca Guarino ; Laura Maria Trillo Asensio 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2020
卷号：12
期号：1
页码：111-124
DOI：10.3390/nu12010111
出版社：MDPI Publishing
摘要：The prevalence of obesity is increasing worldwide, leading to a severe impairment of overall health. Actually, obesity has been associated with several pathological conditions, causing an excess overall mortality. In particular, overweight and obesity are well known risk factors for a variety of gastrointestinal (GI) disorders i.e., functional GI disorders as well as, inflammatory bowel disease (IBD), pancreatitis, and GI cancer. The aim of the present review is to summarize the potential role of overweight and obesity in GI disease with particular focus on plausible biological mechanisms that could explain the association between obesity and GI disease based on the most recent evidence in the literature.
关键词：overweight and obesity; functional gastrointestinal disorders (FGIDs); visceral hypersensitivity; gastrointestinal motility; cancer overweight and obesity ; functional gastrointestinal disorders (FGIDs) ; visceral hypersensitivity ; gastrointestinal motility ; cancer