文章基本信息

标题：Infant Complementary Feeding of Prebiotics for the Microbiome and Immunity
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作者：Starin McKeen ; Wayne Young ; Jane Mullaney 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2019
卷号：11
期号：2
页码：364-386
DOI：10.3390/nu11020364
出版社：MDPI Publishing
摘要：Complementary feeding transitions infants from a milk-based diet to solid foods, providing essential nutrients to the infant and the developing gut microbiome while influencing immune development. Some of the earliest microbial colonisers readily ferment select oligosaccharides, influencing the ongoing establishment of the microbiome. Non-digestible oligosaccharides in prebiotic-supplemented formula and human milk oligosaccharides promote commensal immune-modulating bacteria such as Bifidobacterium, which decrease in abundance during weaning. Incorporating complex, bifidogenic, non-digestible carbohydrates during the transition to solid foods may present an opportunity to feed commensal bacteria and promote balanced concentrations of beneficial short chain fatty acid concentrations and vitamins that support gut barrier maturation and immunity throughout the complementary feeding window.
关键词：weaning; oligosaccharides; non-digestible carbohydrates; metabolites; gut barrier; tolerance weaning ; oligosaccharides ; non-digestible carbohydrates ; metabolites ; gut barrier ; tolerance