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  • 标题:The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility
  • 本地全文:下载
  • 作者:Tugba Ozdal ; David A. Sela ; Jianbo Xiao
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2016
  • 卷号:8
  • 期号:2
  • 页码:78-113
  • DOI:10.3390/nu8020078
  • 出版社:MDPI Publishing
  • 摘要:As of late, polyphenols have increasingly interested the scientific community due to their proposed health benefits. Much of this attention has focused on their bioavailability. Polyphenol–gut microbiota interactions should be considered to understand their biological functions. The dichotomy between the biotransformation of polyphenols into their metabolites by gut microbiota and the modulation of gut microbiota composition by polyphenols contributes to positive health outcomes. Although there are many studies on the in vivo bioavailability of polyphenols, the mutual relationship between polyphenols and gut microbiota is not fully understood. This review focuses on the biotransformation of polyphenols by gut microbiota, modulation of gut microbiota by polyphenols, and the effects of these two-way mutual interactions on polyphenol bioavailability, and ultimately, human health.
  • 关键词:polyphenols; phenolics; flavonoids; gut microbiota; microbial metabolism; bioavailability; health; interactions
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