文章基本信息

标题：Extra Virgin Olive Oil: Lesson from Nutrigenomics
本地全文：下载
作者：Stefania De Santis ; Marica Cariello ; Elena Piccinin 等
期刊名称：Nutrients
电子版ISSN：2072-6643
出版年度：2019
卷号：11
期号：9
页码：2085-2101
DOI：10.3390/nu11092085
出版社：MDPI Publishing
摘要：Extra virgin olive oil (EVOO) consumption has a beneficial effect on human health, especially for prevention of cardiovascular disease and metabolic disorders. Here we underscore the peculiar importance of specific cultivars used for EVOO production since biodiversity among cultivars in terms of fatty acids and polyphenols content could differently impact on the metabolic homeostasis. In this respect, the nutrigenomic approach could be very useful to fully dissect the pathways modulated by different EVOO cultivars in terms of mRNA and microRNA transcriptome. The identification of genes and miRNAs modulated by specific EVOO cultivars could also help to discover novel nutritional biomarkers for prevention and/or prognosis of human disease. Thus, the nutrigenomic approach depicts a novel scenario to investigate if a specific EVOO cultivar could have a positive effect on human health by preventing the onset of cardiovascular disease and/or chronic inflammatory disorders also leading to cancer.
关键词：extra virgin olive oil; polyphenol content; fatty acids; nutrigenomics; human health extra virgin olive oil ; polyphenol content ; fatty acids ; nutrigenomics ; human health