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  • 标题:Choline: Exploring the Growing Science on Its Benefits for Moms and Babies
  • 本地全文:下载
  • 作者:Hunter W. Korsmo ; Xinyin Jiang ; Marie A. Caudill
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2019
  • 卷号:11
  • 期号:8
  • 页码:1823-1837
  • DOI:10.3390/nu11081823
  • 出版社:MDPI Publishing
  • 摘要:The importance of ensuring adequate choline intakes during pregnancy is increasingly recognized. Choline is critical for a number of physiological processes during the prenatal period with roles in membrane biosynthesis and tissue expansion, neurotransmission and brain development, and methyl group donation and gene expression. Studies in animals and humans have shown that supplementing the maternal diet with additional choline improves several pregnancy outcomes and protects against certain neural and metabolic insults. Most pregnant women in the U.S. are not achieving choline intake recommendations of 450 mg/day and would likely benefit from boosting their choline intakes through dietary and/or supplemental approaches.
  • 关键词:choline; placenta; epigenetic programming; pregnancy outcomes; cognitive development choline ; placenta ; epigenetic programming ; pregnancy outcomes ; cognitive development
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